Highlighted Publications
- Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors Nature Communications 3(1), 1288, 2012
- Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug? Open Biology 7(11), 2017
- A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine Nature Communications 9(1), 3116, 2018
- HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase Science Translational Medicine 9(398), eaal5272, 2017
- Site occupancy calibration of taxane pharmacology in live cells and tissues Proceedings of the National Academy of Sciences 115(48), E11406-E11414, 2018
- A scalable pipeline for high-throughput flow cytometry SLAS Discovery 23(7), 708-718, 2018
- Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment Elife 8, e45426
Scientific Presentations
- The RDKit is Getting Rust-y RDKit 13th User Group Meeting. September 11-13, 2024
- Overcoming the Model Sourcing Challenge with the World's Largest Database of Proprietary Tumor Models Discovery on Target 20th Annual Meeting. September 25-28, 2023
- The Disease Model Finder: An AI Powered Platform to Enhance Disease Model Sourcing Tumor Models for Combination Targeted Oncology 10th Annual Meeting. July 13-14, 2022
- Site Occupancy Calibration of Taxane Pharmacology in Live Cells and Tissues EMBO | EMBL Symposia (Microtubules: From Atoms to Complex Systems). May 27-30, 2018
- Using Live-Cell Microscopy and Quantitative Proteomics to Elucidate the Signaling Consequences of Microtubule Disruption American Society of Cell Biology. December 12-16, 2015
- Molecular Dynamics of DOT1L and Modeling of EZH2 Biophysical Society 57th Annual Meeting. February 2-6, 2013